Taking as a starting point the hypotheses that the urban body is a self-adapted ecology made of material and non-material components (Bateson, 1972), relationships between elements are examined in an attempt to destabilize the static division of matter and idea and to inquire into those relationships that determine the structural coupling (Maturana, 2002) between body and environment, as well as the constitution of the body itself. Contemporary technology is used in order to trace these alterations and the urban body is examined as a network configuration. The importance of the methodology adopted by the current research lies in the fact that social and economic factors merge with spatial characteristics, allowing for a visualization and re-interpretation of the urban body mutations based on self-adapted reconfigurations and for a prediction of the structural alterations made possible through the reconfiguration of the synaptic forces between elements.