Contemporary explorations within the evolutionary computational domain have been heavily instrumental in exploring biological processes of adaptation, growth and mutation. On the other hand a plethora of designers owing to the increasing sophistication in computer aided design software are equally enthused by the formal aspects of biological organisms and are thus meticulously involved in form driven design developments. This focus on top-down appearance and surface condition based design development under the banner of organic architecture in essence contributes to the growing misuse of bio-inspired design and the inherent meaning associated with the terminology. HyperCell, a bio-inspired information design framework for real-time adaptive spatial components, is an ongoing research, at Hyperbody, TU Delft, which focuses on extrapolating bottom-up generative design and real-time interaction based adaptive spatial re-use logics by understanding processes of adaptation, multi-performance and self sustenance in natural systems. Evolutionary developmental biology is considered as a theoretical basis for this research.